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EMJ
29th December 2013

Management of Hepatitis B Virus Infection in Liver Transplant Recipients

Hepatitis B virus (HBV)-related liver disease is a common indication for liver transplantation (LT) in Asian countries. When left untreated, the overall…
EMJ
29th December 2013

IL28B Polymorphisms in Interferon-Treated Patients with Chronic Hepatitis B

Pegylated interferon (Peg-IFN) may achieve a sustained off-treatment response in 20-30% of the patients with chronic hepatitis B (CHB).
EMJ
29th December 2013

Cellular Consequences of Z Alpha-1 Antitrypsin Accumulation and Prospects for Therapy

The Z variant (Glu342Lys) of α1-antitrypsin polymerises and accumulates in the hepatocyte endoplasmic reticulum predisposing to neonatal hepatitis…
EMJ
29th December 2013

Acute-On-Chronic Liver Failure: Applying the PIRO Concept

Acute-on-chronic liver failure (ACLF), a clinical syndrome associated with a dismal prognosis, occurs acutely in previously stable cirrhotic patients.
EMJ
29th December 2013

Adrenal Insufficiency (AI) in Cirrhosis

Adrenal dysfunction or insufficiency (AI) in cirrhosis, also described as hepato-adrenal syndrome, is an only recently recognised entity.
EMJ
29th December 2013

Hepatic Encephalopathy: A Paradigm Shift

The most recent understanding of the pathogenesis of hepatic encephalopathy (HE) is that heterogeneous precipitating factors cause a low-grade cerebral…
16th December 2013

Treatment of Hepatic Encephalopathy – Targeting the Gut-Liver-Brain Axis

Summary of Presentations from the Norgine Sponsored Satellite Symposium, UEG Week, Berlin, Germany, 12th–16th October 2013
16th December 2013

State-of-the-Art Treatment of Irritable Bowel Syndrome – Recent Advances and Emerging Therapeutic Alternatives

Irritable bowel syndrome (IBS) is a highly prevalent functional disorder characterised by chronic and recurrent abdominal pain and altered bowel habit.
16th December 2013

Understanding the Pathophysiology of IBS

While irritable bowel syndrome (IBS) is still considered a ‘disorder of gut function’ and is diagnosed on the basis of symptoms, evidence is growing to…
16th December 2013

Practical Evaluation and Handling of Patients with Irritable Bowel Syndrome

Irritable bowel syndrome (IBS) is a functional bowel disorder by unknown aetiology. Several reviews are written about pharmacological and psychological…