Uncategorised - European Medical Journal

Raising the Clinical Bar Beyond Current Biologics in Uncontrolled Persistent Asthma: Translating Emerging Data in Future Clinical Decisions

Asthma is a heterogeneous disease with multiple phenotypes, caused by a complex interplay of inflammatory pathways. Up to 70% of patients with asthma…

Allergy Prevention by Allergens Depends on Their Ligands

The prevalence of allergy in the Western world is increasing, with 35% of women and 24% of men in Germany affected.1 It is unclear why atopic individuals…

Editor’s Pick: Asthma and Food Allergies

There is a long-established link between allergic diseases in atopic individuals, whereby having one atopic condition can predispose that individual to…

Response to Omalizumab in Urticaria and Asthma: Is it a ‘Lifetime Together’ Treatment?

Omalizumab is a recombinant human monoclonal antibody that blocks the immunoglobulin (Ig)E receptor and is indicated in cases of severe asthma (SA)…

The Oligosaccharide Galactose-α-1,3-Galactose and the α-Gal Syndrome: Insights from an Epitope that is Causal in Immunoglobulin E-Mediated Immediate and Delayed Anaphylaxis

Galactose-α-1,3-galactose (α-Gal) is an oligosaccharide that was first described as a cause of immunoglobulin E-mediated anaphylaxis in cases of…

Use of Breathomics in the Diagnosis of Paediatric Patients with Persistent Asthma

In paediatric asthma, symptoms tend to appear during the first 6 years of life and may be associated with different disease phenotypes and endotypes, each…

Allergy to Stinging Insects: Diagnosis and Management

Stinging insects that cause allergic reactions belong to the order Hymenoptera, which includes wasps, hornets, bees, yellow jackets, true hornets, and…

Malignancies as the Main Cause of Death in Common Variable Immunodeficiency: An Italian Multicentre Study

Cancer immunosurveillance is a major function of the immune system. Strong evidence for the role of the immune system in antitumour surveillance…

Autoinflammatory Diseases: Consequences of Uncontrolled Inflammasome Activation

Inflammasomes are sensors within the innate immune system that are responsible for the regulation of caspase-1 activation and the initiation of…

Genetically Modified Wheat, Wheat Intolerance, and Food Safety Concerns

Wheat intolerance is a common problem for certain individuals. A gluten-free diet is the only option for people with wheat-associated disorders (WAD) to…