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EMJ Hematology US 1.1 2020
2 Mins
24 Jan 2020

Fli-1 Transcriptionally Integrates Microenvironmental Cues Sensing by Self-Renewing Haematopoietic Stem and Progenitor Cells

During adulthood and embryogenesis, fate decisions of haematopoietic stem and progenitor cells (HSPC), such as specification, self-renewal, and…
13 Mins
24 Jan 2020

Review of the American Society of Hematology (ASH) Congress 2019

The City Beautiful” proved to be an appropriate nickname for Orlando, Florida, USA, where the sun shined as >30,000 attendees flocked to attend this…
9 Mins
24 Jan 2020

ASH 2019 Interviews

We spoke to Prof Theresa L. Coetzer, the Chair of the ASH International Members Committee, and Dr Pierluigi Porcu, the Chair of ASH Foundation…
EMJ Hematology US 1.1 2020
2 Mins
24 Jan 2020

Novel CD33 Antibodies Reveal CD33 Splicing Polymorphism Variant Localisation and Therapeutic Implications

Acute myeloid leukaemia (AML) is a heterogeneous haematologic malignancy characterised by dysfunctional proliferation and differentiation of myeloid progenitor cells.
EMJ Hematology US 1.1 2020
9 Mins
24 Jan 2020

Therapeutic Options in Myelodysplastic Syndromes Following Hypomethylating Agent Failure

Myelodysplastic syndromes (mds) are a heterogeneous group of disorders defined by ineffective haematopoiesis and clonal instability with risk of…
EMJ Hematology US 1.1 2020
4 Mins
24 Jan 2020

Reed Sternberg-Like Cells in an Aggressive Lymphoma: Report of a Rare Case and Review of Literature

In low-grade B-cell lymphomas, Reed Sternberg (RS)-like cells can be seen in follicular lymphoma, chronic lymphocytic leukemia/small lymphocytic lymphoma, and marginal zone lymphoma.
EMJ Hematology US 1.1 2020
2 Mins
24 Jan 2020

Safety and Efficacy of 1,020 mg Total Dose Infusion of Ferumoxytol in a Veterans Health System

Ferumoxytol is an intravenous (IV) formulation of iron that can be infused quickly, making it a convenient choice.
EMJ Hematology US 1.1 2020
1 Mins
24 Jan 2020

Assessment of Mortality and its Associated Risk Factors in Patients with Transfusion-Dependent Thalassaemia in India

India is home to approximately 100,000 people living with transfusion-dependent severe thalassaemia,1 and yet very little data on survival are available…
EMJ Hematology US 1.1 2020
11 Mins
24 Jan 2020

Pernicious Anaemia: Mechanisms, Diagnosis, and Management

Pernicious anaemia (PA) is an autoimmune disease of multifactorial aetiology involving environmental and immunological factors. It is the most common cause of cobalamin deficiency anaemia worldwide.
EMJ Hematology US 1.1 2020
2 Mins
24 Jan 2020

Lactate Release by Inflammatory Bone Marrow Neutrophils Induces their Mobilisation via Endothelial GPR81 Signalling

Innate immune neutrophils provide the first line of host defence against bacterial infections.