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8 Mins
23 Jul 2020

Editor’s Pick: New Aspects of Pathogenesis and Treatment of Membranous Glomerulopathy After the MENTOR Study

Membranous nephropathy (MN) is the major cause of nephrotic syndrome in adults, accounting for 20% of cases with an annual incidence of 1 per 100,000 population.
4 Mins
23 Jul 2020

The Hidden Cost of Repair: Cancer Risk Following Kidney Injury

INJURY to renal cells can lead to the development of papillary renal cell carcinoma (RCC) via the kidney’s own repair mechanisms. Leading nephrologist…
3 Mins
23 Jul 2020

Chronic Kidney Disease Classification: Past, Present, and Future

CHRONIC kidney disease (CKD), a long-term condition resulting in the gradual loss of kidney function, is surrounded by debate regarding validity…
4 Mins
23 Jul 2020

Pharmacokinetics of Ceftriaxone During Prolonged Intermittent Renal Replacement Therapy in a Patient with Child–Pugh B Cirrhosis and Ascites

Prolonged intermittent renal replacement therapy (PIRRT) is emerging as an alternative to continuous renal replacement therapy as renal support for the critically ill.
1 Mins
23 Jul 2020

Mepolizumab Therapy in Eosinophilic Granulomatosis with Polyangiitis: 1-Year Follow-Up Study Using Anti-IL-5 as a Steroid Sparing Therapeutic Approach

Eosinophilic granulomatosis with polyangiitis (EGPA) is a small vessel vasculitis characterised by the presence of tissue eosinophilia…
10 Mins
23 Jul 2020

Acute Kidney Injury: Risk Factors and Management Challenges in Low- and Middle-Income Countries

Acute kidney injury (AKI) is a major global health problem, occurring in >13 million people and responsible for >2.3 million deaths every year, 85% of which are in developing countries.
2 Mins
23 Jul 2020

Use of Rituximab for Glomerular Diseases Indicated Versus Off-Label: Clinical Perspective

Rituximab (RTX) is used worldwide for the treatment of glomerulonephritis (GN), including membranous glomerulopathy (MN), minimal change disease (MCD)…
10 Mins
23 Jul 2020

Diabetic Kidney Disease in Childhood and Adolescence: Conventional and Novel Renoprotective Strategies

Diabetic kidney disease (DKD) is defined as a clinical syndrome consisting of persistent macroalbuminuria
5 Mins
23 Jul 2020

Pharmacokinetics of Amoxicillin and Cefepime During Prolonged Intermittent Renal Replacement Therapy: A Case Report

Prolonged intermittent renal replacement therapy (PIRRT) is an emerging form of renal replacement therapy in critically ill patients, but dosing data…
2 Mins
23 Jul 2020

Chronic Interstitial Nephritis in Agricultural Communities: A Toxin-Induced Proximal Tubular Nephropathy

In the early 1990s, clinicians in Central America and Sri Lanka noticed an upsurge of chronic kidney disease (CKD) in agricultural communities…