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EMJ 5.3 2020
7 Mins
17 Sep 2020

Digit-all: Rare Diseases

Rare diseases are increasingly recognised as a global public health priority.1 Whilst rare diseases have a low prevalence individually, it is estimated…
7 Mins
17 Sep 2020

Editor's Pick: Tumour-Associated Hypoxia: Can We Give Chimeric Antigen Receptor T Cells More Breathing Space?

Chimeric antigen receptors (CAR) are fusion molecules that couple the binding of a native tumour-associated target to the delivery of a bespoke T…
5 Mins
17 Sep 2020

Superficial Ulcerating Rheumatoid Necrobiosis Associated with Methotrexate Use in a Patient with Rheumatoid Arthritis

Rheumatoid arthritis (RA) is a systemic autoimmune condition prevalent in North America and Northern European populations with an incidence of 1%…
9 Mins
17 Sep 2020

Economic Evaluation of Severe Anaemia

Anaemia is characterised by a decrease in the total amount of red blood cells (RBC) and haemoglobin (Hb) levels, reducing the volume of oxygen transported through the blood…
9 Mins
17 Sep 2020

Metastasis: A Bane of Breast Cancer Therapy

Breast cancer is one of the most commonly diagnosed cancers among women.1 Despite advances in treatment for breast cancer…
6 Mins
17 Sep 2020

Sjögren’s Syndrome Complicated with Type 2 Autoimmune Hepatitis: A Case Report-Based Review of the Literature

Autoimmune hepatitis is a condition closely related to autoimmune diseases. Previously, it was known to have three distinct types, which were recently…
7 Mins
17 Sep 2020

The Benefits of Testosterone Therapy in Poor Ovarian Responders Undergoing In Vitro Fertilisation (IVF)

The most challenging patients for fertility care providers are the poor ovarian responders (POR)…
10 Mins
17 Sep 2020

What Makes the Lung Unique – Tissue-Specific Immunity in the Respiratory Tract

As the mediator of gas exchange, the lung is an essential organ for mammalian survival and has thus evolved a diverse and intricate set of defence…
11 Mins
17 Sep 2020

Treatment of Interstitial Cystitis/Bladder Pain Syndrome: A Contemporary Review

Interstitial cystitis/bladder pain syndrome (IC/BPS), is among one of the most common diagnoses that give rise to chronic pelvic pain…
12 Mins
17 Sep 2020

Putting into Perspective the Future of Cancer Vaccines: Targeted Immunotherapy

Cancer is a genetic and epigenetic disease of multicellularity, driving transformed cells to uncontrolled growth, invasion, and metastasis. In cancer, intracellular mechanisms controlling cellular proliferation are damaged first, which allows certain cells to progress to malignant transformation…