Uncategorised - European Medical Journal

TRAILBLAZER-ALZ Trial Data Reveals Donanemab Effects in Early Alzheimer's: AAN 2025

At the 2025 American Academy of Neurology (AAN) Annual Meeting in San Diego, new data from the TRAILBLAZER-ALZ clinical trial program highlighted critical risk factors and management strategies for amyloid-related imaging abnormalities (ARIA) in patients with early symptomatic Alzheimer’s disease treated with donanemab.

EBMT 2025: Long-Term Outcomes of CAR-T Cell Therapy in Relapsed Lymphoma

A study at EBMT 2025 shows improved outcomes for relapsed lymphoma patients using CAR-T cell therapy with stem cell transplantation.

EBMT 2025: Stem Cell Treatment for Early-Onset IBD

HSCT shows promising results as a cure for very early-onset inflammatory bowel disease caused by IL-10 receptor deficiency.

Targeting Senescent Cells to Treat MASLD Effectively

Recent studies have identified a gene signature known as the senescent hepatocyte gene signature that tracks with MASLD progression.

EBMT 2025: Transplantation Outcomes in MDS/AML

Explore EBMT 2025 results on transplantation outcomes for Myelodysplastic Syndrome and Acute Myeloid Leukaemia, highlighting survival and relapse data.

EBMT 2025: Adoptive Cell Therapy for Infections in Immunocompromised

Adoptive cell therapy with memory T lymphocytes clears infections in patients that are immunocompromised, showing promising results at EBMT 2025.

EBMT 2025: Are Functional Respiratory Tests Key for Screening in CAR-T Cell Therapy?

Functional respiratory tests may help predict outcomes in anti-CD19 CAR-T cell therapy, as shown in EBMT 2025 research.

EBMT 2025: Maintenance Therapy Improves High-Risk AML Outcomes

Maintenance therapy significantly boosts outcomes for high-risk AML patients after transplantation, as highlighted at EBMT 2025.

Landmark Migraine Study Identifies 778 Genetic Risk Variants in Veterans: AAN 2025

A genome-wide association study (GWAS) presented at the 2025 American Academy of Neurology (AAN) Annual Meeting in San Diego has identified 778 previously unknown genetic variants associated with migraine, shedding new light on the condition’s genetic underpinnings across racial and ethnic groups.

How Clinicians’ Expectations Shape AI Diagnostic Tools’ Success

New research has examined what drives clinicians to adopt intelligence-enabled diagnostic clinical decision support systems, and how to improve uptake.