louisakewell, Author at European Medical Journal - Page 18 of 153

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6 Mins
20 Nov 2018

Editor's Pick: How Can We Develop More Effective Strategies for Type 2 Diabetes Mellitus Prevention? A Paradigm Shift from a Glucose-Centric to a Beta Cell-Centric Concept of Diabetes

This thought-provoking paper by Saisho provides a very accessible discussion of the shift from a glucose-centric to a beta cell-centric understanding…
2 Mins
20 Nov 2018

Abdominal Subcutaneous Adipose Tissue Gene Expression in Relation to Tissue-Specific Insulin Resistance in Human Obesity

Obesity and being overweight are major risk factors for several diseases, including cardiovascular disease and Type 2 diabetes mellitus. Adipose tissue…
11 Mins
20 Nov 2018

Update on the Management of Diabetic Dyslipidaemia

Diabetic dyslipidaemia is characterised by low levels of HDL-C, elevated levels of LDL-C, and a high prevalence of small dense LDL particles
9 Mins
20 Nov 2018

Efficacy of Wearable Devices to Measure and Promote Physical Activity in the Management of Diabetes

Physical inactivity is a global health problem that contributes to the increasing risk of obesity and diabetes. Wearable devices are defined as…
2 Mins
20 Nov 2018

Variants in Genes (DHCR7, CYP2R1, and GC) Regulating Vitamin D Metabolism Determine Low Vitamin D Levels in Type 2 Diabetic Patients

Hypovitaminosis D is associated with an increased prevalence and incidence of metabolic syndrome and Type 2 diabetes mellitus (T2DM).
2 Mins
20 Nov 2018

High Low-Density Lipoprotein Cholesterol Levels and Risk of Peripheral Vascular Diseases: A Mendelian Randomisation Study Including 116,419 Individuals From The General Population

High low-density lipoprotein (LDL) cholesterol levels are causally involved in the pathogenesis of atherosclerosis and are related to an increased risk…
10 Mins
20 Nov 2018

Low-Carbohydrate Diets and Glycaemic Control in Type 1 Diabetes Mellitus

In recent years the successful treatment of Type 2 diabetes mellitus through total calorific and/or dietary carbohydrate restriction has been well…
11 Mins
20 Nov 2018

Growth Hormone and Metabolic Homeostasis

This review provides an overview of the effects of pituitary growth hormone (GH) on glucose, lipid, and protein metabolism, insulin resistance, and metabolic homeostasis.
2 Mins
20 Nov 2018

Inhibition of Insulin Secretion by Cxcl14

G protein-coupled receptors are tractable targets for pharmacotherapies;1 however, challenges arise when it is necessary to either deorphanise a known…
10 Mins
20 Nov 2018

Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitors: Efficacy and Safety in the Treatment of Hypercholesterolaemia

Proprotein convertase subtilisin/kexin type 9 inhibitors (PCSK9I) are a new class of medication that has recently arisen to combat hypercholesterolaemia.