A NOVEL endoscopic approach combining loop-assisted inversion with double suturing has shown high success in removing gastric fundal subepithelial lesions, according to a new study.
In this retrospective analysis, researchers assessed 12 patients with 14 gastric fundal lesions, primarily gastrointestinal stromal tumours (GISTs) and leiomyomas, who underwent the procedure between January 2023 and January 2024. The findings revealed a 100% surgical success rate, with no intraoperative complications, postoperative bleeding, or need for antibiotics.
All tumours were completely resected using the minimally invasive technique. Notably, no patients required open surgery, and no recurrences were observed during the follow-up period. Most lesions were classified as low-risk G1 GISTs, a category that typically has a favourable prognosis when removed early.
The loop-assisted inversion and double suture technique is designed to improve access and visibility during endoscopic tumour removal in hard-to-reach areas like the gastric fundus. Researchers emphasized that the method is safe, effective, and time-saving, but noted that larger, multicentre prospective studies are needed to validate its long-term outcomes.
Aleksandra Zurowska, EMJ
Reference
Tao Z et al. A new endoscopic treatment for gastric fundal subepithelial lesions using loop-assisted inversion and double suture technique. Sci Rep. 2025;DOI: 10.1038/s41598-025-94749-w.
