ECC 2015: Genetic screening of brain metastases may reveal new targets for treatment

Genetic analysis of biopsies taken from the primary tumour, brain metastases and normal tissues of 104 adults with cancer found that, in every patient, the brain metastasis and primary tumour shared some of their genetics, but there were key differences. In 56% of patients, genetic alterations that potentially could be targeted with drugs were found in the brain metastasis but not in the primary tumour. In addition, it was found that if a patient had more than one brain metastasis, each was genetically similar.

Presented at the European Cancer Conference (ECC) 2015 by Priscilla Kaliopi Brastianos, MD, of Dana-Farber Cancer Institute, Boston, MA

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