Update: Diagnosis and Treatment of Muscle- Invasive and Metastatic Bladder Cancer in 2014

*Johannes Br√ľndl, Philipp J. Spachmann, Maximilian Burger

Department of Urology, University of Regensburg, Caritas St. Josef Medical Center, Regensburg, Germany *Correspondence to johannes.bruendl@ukr.de

Disclosure: No potential conflict of interest.


Bladder cancer (BC) is the ninth most commonly diagnosed malignant tumour in the world, with an incidence of about 356,000 and a mortality of about 145,000 per year in both non-muscle-invasive and muscle-invasive BC. Although a high percentage of urothelial cancers of the bladder are staged as non- muscle-invasive, muscle invasion can already be found in about 30% of all patients at the time of initial diagnosis. The intention of the following article is to give an overview of the diagnosis and treatment of muscle-invasive and metastatic BC according to the latest update of the EAU (European Association of Urology) guidelines.

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