Ankylosing Spondylitis: A Review

Farrouq Mahmood,1 *Philip Helliwell2

1. Bradford Teaching Hospitals, Bradford, UK
2. Leeds and Bradford Teaching Hospitals, Bradford, UK
*Correspondence to

Disclosure: The authors have declared no conflicts of interests.
Received: 28.02.17 Accepted: 15.08.17
Citation: EMJ. 2017;2[4]:134-139.


Ankylosing spondylitis is a chronic autoimmune inflammatory condition belonging to the spondyloarthropathy category of rheumatic diseases. It typically affects the axial skeleton but may also present with peripheral arthritis and extra-articular features. Ankylosing spondylitis tends to occur in patients under the age of 45 years, has a higher incidence in males, and can lead to disability and reduced quality of life if not adequately treated. Management consists of a multidisciplinary team approach. Although traditional disease modifying anti-rheumatic drugs are less effective for the axial component of this disease, biologic therapies do seem effective. In severe cases, surgery may be warranted.

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