Re: State-Of-The-Art Treatment in Castration-Resistant Prostate Cancer – Forward to the past – Again

Re: State-Of-The-Art Treatment in Castration-Resistant Prostate Cancer – Forward to the past – Again

May 7, 2015 at 9:23 AM 0 comments

*Hannah C.P. Wilson, S. Imran A. Shah, Patricia Price, Paul D. Abel Department of Surgery and Cancer, Imperial College London, B-Block Hammersmith Campus, London, UK *Correspondence to hannah.wilson12@imperial.ac.uk Letter in response to: Castro E. et al. State-of-the-art treatment in castration-resistant prostate cancer. EMJ Oncol. 2014;2:100-5. Castro E. et al. choseRead More

Editor’s Pick: Paradigm Shift in the Management of Gynaecological Cancers

Editor’s Pick: Paradigm Shift in the Management of Gynaecological Cancers

March 17, 2015 at 9:56 AM 0 comments

My paper selection is ‘Paradigm shift in the management of gynaecological cancers’ by Sap and Van Trappen. This paper is of interest because it summarises the advances in the management of gynaecological cancers. More importantly it emphasises a multidisciplinary approach to  these tumours, which not only improves the outcome butRead More

Field Cancerisation of the Upper Aerodigestive Tract: Screening for Second Primary Cancers of the Oesophagus in Cancer Survivors

Field Cancerisation of the Upper Aerodigestive Tract: Screening for Second Primary Cancers of the Oesophagus in Cancer Survivors

March 17, 2015 at 9:54 AM 0 comments

*Hans Scherübl,1 Güllü Cataldegirmen,2 Jan Eick,1 Wanda Ring,1  Christoph Schwertner,1 Joachim  Steinberg,1 Hermann Herbst3 1. Klinik für Gastroenterologie, GI Onkologie und Infektiologie, Vivantes Klinikum Am Urban,  Berlin, Germany 2. Klinik für Viszeral- und Gefäßchirurgie, Vivantes Auguste-Viktoria-Klinikum, Berlin, Germany 3. Institut für Pathologie, Vivantes – Netzwerk für Gesundheit, Berlin, Germany *CorrespondenceRead More

Perspectives in Surgery of Oligometastatic Non-Small-Cell Lung Cancer

Perspectives in Surgery of Oligometastatic Non-Small-Cell Lung Cancer

March 17, 2015 at 9:49 AM 0 comments

*Fabio Villa, Barberá Carbonell Beatriz, Stefano Cafarotti Ospedale Regionale di Bellinzona e Valli, Bellinzona, Switzerland *Correspondence to fabiovilla210486@gmail.com Disclosure: No potential conflict of interest. Received: 08.10.14 Accepted: 26.01.15 Citation: EMJ Oncol. 2015;3[1]:29-33. Abstract 20-50% of patients with newly diagnosed non-small-cell lung cancer (NSCLC) have synchronous metastases. This dramatically affects survivalRead More

Symptoms and Quality of Life in Gastroenteropancreatic Neuroendocrine Tumours

Symptoms and Quality of Life in Gastroenteropancreatic Neuroendocrine Tumours

March 17, 2015 at 9:45 AM 0 comments

Sebastian Kaupp-Roberts,1 Rajaventhan Srirajaskanthan,2 *John K. Ramage1,2 1. Department of Gastroenterology and Hepatology, Hampshire Hospitals  NHS Foundation Trust, Basingstoke, UK 2. Neuroendocrine Tumour Service, Institute of Liver Studies, King’s College Hospital, London, UK *Correspondence to john.ramage@hhft.nhs.uk Disclosure: No potential conflicts of interest. Received: 28.11.14 Accepted: 26.01.15 Citation: EMJ Oncol. 2015;3[1]:34-40. AbstractRead More

Recent Advances in Definitive Radiotherapy for Prostate Cancer

Recent Advances in Definitive Radiotherapy for Prostate Cancer

March 17, 2015 at 9:40 AM 0 comments

*Michael Pinkawa Department of Radiation Oncology, RWTH Aachen University, Aachen, Germany *Correspondence to MPinkawa@ukaachen.de Disclosure: No potential conflict of interest. Received: 27.10.14 Accepted: 17.12.14 Citation: EMJ Oncol. 2015;3[1]:41-48. Abstract Definitive radiation therapy is a well-recognised curative treatment option for localised prostate cancer. A suitable technique, dose, target volume, and theRead More

Development of Drugs Targeting the PI3K Signalling Pathway in Leukaemias and Lymphomas

Development of Drugs Targeting the PI3K Signalling Pathway in Leukaemias and Lymphomas

March 17, 2015 at 9:36 AM 0 comments

*Alexandre Arcaro Department of Clinical Research, Division of Pediatric Hematology/Oncology, University of Bern, Bern, Switzerland *Correspondence to alexandre.arcaro@dkf.unibe.ch Disclosure: The author declares no conflict of interest. Received: 17.10.14 Accepted: 22.01.15 Citation: EMJ Oncol. 2015;3[1]:49-58. Abstract The phosphoinositide 3-kinase (PI3K) family of signalling enzymes play a key role in the transductionRead More

Alloimmune Thrombocytopaenic Disorders: A Review

Alloimmune Thrombocytopaenic Disorders: A Review

March 17, 2015 at 9:33 AM 0 comments

*Sophia Delicou, Marianna Bellia Thalassemia and Transfusion Unit, Hippokrateion General Hospital of Athens, Athens, Greece *Correspondence to sophiadelicou@gmail.com Disclosure: Both authors declare no support from any organisation for the submitted work; no financial relationships in the previous 3 years with any organisations that might have an interest in the submittedRead More

Multiple Myeloma and Renal Failure

Multiple Myeloma and Renal Failure

March 17, 2015 at 9:30 AM 0 comments

*Patrizia Tosi, Manuela Imola, Anna Maria Mianulli,  Simona Tomassetti, Annalia Molinari, Serena Mangianti,  Marina Ratta, Anna Merli, Valentina Polli Hematology Unit, Department of Oncology and Hematology, Infermi Hospital, Rimini, Italy *Correspondence to patrizia.tosi@auslrn.net Disclosure: No potential conflict of interest. Received: 04.11.14 Accepted: 30.12.14 Citation: EMJ Oncol. 2015;3[1]:65-69. Abstract Renal failureRead More

Checkpoint Blockade in Cancer Immunotherapy: Squaring the Circle

Checkpoint Blockade in Cancer Immunotherapy: Squaring the Circle

March 17, 2015 at 9:27 AM 0 comments

*Maria A.V. Marzolini, Sergio A. Quezada, Karl S. Peggs UCL Cancer Institute, University College London, London, UK *Correspondence to m.marzolini@ucl.ac.uk Disclosure: No potential conflict of interest. Received: 11.11.14 Accepted: 12.12.14 Citation: EMJ Oncol. 2015;3[1]:70-76. Abstract Manipulating the complex interaction between the immune system and tumour cells has been the focusRead More