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Recent Developments in Regorafenib Treatment for Gastrointestinal Cancers: Presentations at the 2016 Meeting of the European Society for Medical Oncology (ESMO) Congress 2016

Recent Developments in Regorafenib Treatment for Gastrointestinal Cancers: Presentations at the 2016 Meeting of the European Society for Medical Oncology (ESMO) Congress 2016

December 13, 2016 at 8:26 AM 0 comments

Axel Grothey,1 Gerald Prager,2 *Jean-Yves Blay3 1. Mayo Clinic, Mayo Clinic College of Medicine, Rochester, Minnesota, USA 2. Department of Medicine I, Comprehensive Cancer Center Vienna, Medical University Vienna, Vienna, Austria 3. Centre Léon Bérard, Université Claude Bernard Lyon 1, Lyon, France *Correspondence to jean-yves.blay@lyon.unicancer.fr Disclosure: Prof Jean-Yves Blay hasRead More

State-of-the-Art Integration of Multiple Kinase Inhibitors in the Treatment of Gastrointestinal Cancers

State-of-the-Art Integration of Multiple Kinase Inhibitors in the Treatment of Gastrointestinal Cancers

November 22, 2016 at 8:29 AM 0 comments

This satellite symposium took place on 4th September 2016 as a part of the European Society of Medical Oncology (ESMO) Congress in Copenhagen, Denmark Chairperson: Axel Grothey1 Speakers: Marc Ychou,2 Jean-Yves Blay,3 Eric Van Cutsem,4 Jordi Bruix5 1. Mayo Clinic, Rochester, Minnesota, USA 2. Montpellier Cancer Institute, Montpellier, France 3.Read More

Optimising Salvage Therapy in Aggressive B Cell Non-Hodgkin Lymphoma

Optimising Salvage Therapy in Aggressive B Cell Non-Hodgkin Lymphoma

November 22, 2016 at 8:28 AM 0 comments

This symposium took place on 7th October 2016 as a part of the European Society for Medical Oncology (ESMO) 2016 Congress in Copenhagen, Denmark Chairpersons: Francesco D’Amore,1 Ruth Pettengell2 Speakers: Pieternella Lugtenburg,3 Ruth Pettengell,2 Pier Luigi Zinzani,4 Raul Cordoba5 1. Aarhus University Hospital, Aarhus, Denmark 2. St George’s, University ofRead More

Cabozantinib as First-Line Therapy for Patients with Metastatic Renal Cell Carcinoma with Poor or Intermediate-Risk Characteristics

Cabozantinib as First-Line Therapy for Patients with Metastatic Renal Cell Carcinoma with Poor or Intermediate-Risk Characteristics

November 22, 2016 at 8:27 AM 0 comments

This Presidential Symposium took place on 10th October 2016 as a part of the European Society for Medical Oncology (ESMO) Congress in Copenhagen, Denmark Speaker: Toni K. Choueiri Dana-Farber Cancer Institute, Boston, Massachusetts, USA Disclosure: Associate Prof Choueiri has received honoraria for advisory board membership and consultancy from Pfizer, Exelixis,Read More

Regorafenib in Metastatic Colorectal Cancer and Advanced Soft Tissue Sarcomas

Regorafenib in Metastatic Colorectal Cancer and Advanced Soft Tissue Sarcomas

November 22, 2016 at 8:26 AM 0 comments

Summary of Presentations from the 2016 Meeting of The American Society of Clinical Oncology (ASCO) held in Chicago, Illinois, USA, from 3rd–7th June 2016 Speakers: Eric Van Cutsem,1 Yuji Miaymoto,2 Tanios Bekaii-Saab,3 Nicolas Penel4 1. University Hospitals Leuven, Leuven, Belgium 2. Division of Medical Oncology, USC Norris Comprehensive Cancer Center,Read More

Editor’s Pick: Muscle Dysfunction in Childhood Cancer: Biological Mechanisms and Implications for Long-Term Survivorship

Editor’s Pick: Muscle Dysfunction in Childhood Cancer: Biological Mechanisms and Implications for Long-Term Survivorship

November 22, 2016 at 8:25 AM 0 comments

Paediatric oncology therapy has advanced significantly; this improvement is in large part due to experimental treatments and therapies. Nielsen et al. deliver a fascinating piece for this year’s EMJ Oncology eJournal, providing an in-depth review of some of the implications of paediatric cancer treatments in terms of complications in laterRead More

The Importance of Mutational Analysis in Chronic Myeloid Leukaemia for Treatment Choice

The Importance of Mutational Analysis in Chronic Myeloid Leukaemia for Treatment Choice

November 22, 2016 at 8:24 AM 0 comments

*Hugues de Lavallade,1,3 Aytug Kizilors2,3 1. Department of Haematological Medicine, King’s College Hospital NHS Foundation Trust, London, UK 2. Laboratory for Molecular Haemato-Oncology, King’s College Hospital NHS Foundation Trust/King’s College London, London, UK 3. Haematology Department, King’s College London, London, UK *Correspondence to h.delavallade@nhs.net Disclosure: Hugues de Lavallade received research fundingRead More

Modern Indications for Endoscopic Endonasal Surgery

Modern Indications for Endoscopic Endonasal Surgery

November 22, 2016 at 8:23 AM 0 comments

*Samuel M. Lipski,1,2 Antoine Digonnet,1 Pierre Dolhen2 1. Head and Neck Department, Jules Bordet Institute, Free University of Brussels, Brussels, Belgium 2. Ear Nose Throat Department, Tivoli University Hospital, Free University of Brussels, Brussels, Belgium *Correspondence to sam@lipski.be Disclosure: The authors have declared no conflicts of interest. Received: 01.03.16 Accepted: 21.07.16Read More

microRNAS in Therapy Resistance of Breast Cancer

microRNAS in Therapy Resistance of Breast Cancer

November 22, 2016 at 8:22 AM 0 comments

Janine Jung, Vinona Wagner, *Cindy Körner Division of Molecular Genome Analysis, German Cancer Research Center (DKFZ) Heidelberg, Heidelberg, Germany *Correspondence to c.koerner@dkfz-heidelberg.de Disclosure: The authors have declared no conflicts of interests. Received: 29.09.16 Accepted: 07.11.16 Citation: EMJ Oncol. 2016;4[1]:103-112. Abstract Breast cancer is one of the deadliest cancer types worldwideRead More

Gastrointestinal Stromal Tumours: A Review on Genetics, Pathology, Risk Stratification, Clinical Characteristics, Investigation, and Treatment

Gastrointestinal Stromal Tumours: A Review on Genetics, Pathology, Risk Stratification, Clinical Characteristics, Investigation, and Treatment

November 22, 2016 at 8:21 AM 0 comments

*Md Tanveer Adil,1,2 Jayesh Sagar,1 Partha Das,1 Vigyan Jain2 1. Department of Colorectal Surgery, Luton and Dunstable University Hospital, Luton, UK 2. Department of Upper GI Surgery, Luton and Dunstable University Hospital, Luton, UK *Correspondence to tanveer.cmc@gmail.com Disclosure: The authors have declared no conflicts of interest. Received: 26.07.16 Accepted: 24.10.16Read More