Tubular Handling of Uric Acid and Factors Influencing Its Renal Excretion: A Short Review

*Cosimo Marcello Bruno,1 Gabriele Pricoco,1 Damiano Cantone,1 Elisa Marino,1 Francesca Bruno2

1. Department of Clinical and Experimental Medicine, Section of Internal and Emergency Medicine, University of Catania, Catania, Italy
2. Department of Clinical and Experimental Medicine, Section of Nephrology, University of Catania, Catania, Italy
*Correspondence to cmbruno@unict.it

Disclosure: The authors have declared no conflicts of interest.
Received: 11.03.16 Accepted: 26.05.16
Citation: EMJ Nephrol. 2016;4[1]:92-97.

Abstract

In this review, the authors briefly examine the most recent evidence concerning the role of several proteins involved in tubular urate transport. They also analyse the influence of extracellular volume, electrolyte disorders, acid-base imbalance, and insulin-resistance on renal clearance of uric acid.

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