Current Status And Future Perspectives On Drug-Eluting Bioresorbable Coronary Scaffolds: Will The Paradigm Of PCI Shift?

*Alfonso Ielasi, Maurizio Tespili

Division of Cardiology, Bolognini Hospital, Seriate (BG), Italy
*Correspondence to alielasi@hotmail.com

Disclosure: No potential conflict of interest.
Received: 16.01.14 Accepted: 28.02.14
Citation: EMJ Int Cardiol. 2014;1:81-90.

Abstract

Despite improvements in stent platform, polymer, and drug elution, the permanent metallic stents have significant limitations as they distort vessel physiology, predispose to late thrombosis, and may preclude surgical revascularisation. Bioresorbable scaffold (BRS) technology has evolved over the last few years to overcome these drawbacks. Actually, different BRS are either available or under clinical and preclinical investigation. However, the use of BRS has largely been restricted to patients recruited into clinical trials with a relatively small number of ‘real-world’ patients treated with these devices. Here, we highlight the potentialities of these devices, describe the evidence from the recent clinical trials, and discuss the potential advantages as well as challenges that this novel technology may face in routine clinical practice.

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