Surgical Department, Vestre Viken Hospital Trust, Drammen, Norway.
*Correspondence to firstname.lastname@example.org
Disclosure: The author has declared no conflicts of interest.
Received: 05.02.16 Accepted: 10.03.16
Citation: EMJ. 2016;1:76-83.
Colorectal liver metastases (CLM) are the most common hepatic malignancy and are caused by disseminated tumour cells (DTCs) seeded early in the tumourigenesis of colorectal cancer. Despite optimal treatment, CLM are associated with high mortality rates. This review provides an overview of three promising strategies to extend survival in CLM: treatment of DTCs, immunotherapy, and new surgical resection techniques.