Inherited Thrombocytopaenias: Beyond the Bleeding

Inherited Thrombocytopaenias: Beyond the Bleeding

December 11, 2014 at 3:40 PM 0 comments

*Patrizia Noris Department of Internal Medicine, IRCCS San Matteo Foundation; University of Pavia, Pavia, Italy *Correspondence to p.noris@smatteo.pv.it Disclosure: No potential conflict of interest. Abstract The improvement of molecular biology technologies and the increasing number of researchers interested in inherited thrombocytopaenias (ITs) has led to a significant expansion in knowledgeRead More

Inherited Bone Marrow Failure Syndromes with Pancytopaenia

Inherited Bone Marrow Failure Syndromes with Pancytopaenia

December 1, 2014 at 11:56 AM 0 comments

*Sophia Delicou,1 Marianna Bellia,1 Theoni Kanellopoulou,1 Chryssanthi Kontaxi,1 Apostolos Zografakis,2 Konstantinos Maragkos1 1. Thalassemia and Transfusion Unit, Hippokration Hospital of Athens, Athens, Greece 2. Orthopaedics Clinic, Laikon Hospital of Athens, Athens, Greece *Correspondence to sophiadelicou@gmail.com Disclosure: The authors declare no potential conflict of interest. Abstract Bone marrow failure (BMF) isRead More

Biosimilars in Hematology: Increasing Choice, Expanding Access

Biosimilars in Hematology: Increasing Choice, Expanding Access

July 31, 2014 at 10:20 AM 0 comments

Summary of Presentations from the Sandoz Biopharmaceuticals-Sponsored Educational Session, which was part of the ‘Updates-in-Hematology’ Programme, held at the 19th EHA Congress, Milan, Italy, on 11th June 2014 Chairperson: Pier Luigi Zinzani1 Speakers: Joerg Windisch,2 Steffen Thirstrup,3 Wojciech Jurczak,4 Paul Cornes5 1. Institute of Hematology and Medical Oncology ‘L. eRead More

Next Steps in Front-Line Treatment of Lymphoma: The Road Ahead

Next Steps in Front-Line Treatment of Lymphoma: The Road Ahead

July 31, 2014 at 10:13 AM 0 comments

Summary of Presentations from the Celgene-Sponsored Satellite Symposium, held at the 19th EHA Congress, Milan, Italy, on 12th June 2014 Chairperson: Pier Luigi Zinzani1 Speakers: Bruce Cheson,2 Andrew Zelenetz,3 Martin Dreyling,4 Bertrand Coiffier5 1. S. Orsola-Malpighi Hospital, Bologna, Italy 2. Georgetown University Hospital, Washington, DC, USA 3. Memorial Sloan-Kettering CancerRead More

The Multiple Facets of Thrombotic Microangiopathies

The Multiple Facets of Thrombotic Microangiopathies

July 31, 2014 at 10:08 AM 0 comments

Summary of Presentations from the Alexion-Sponsored Symposium, held at the 19th EHA Congress, Milan, Italy, on 12th June 2014 Chairperson: Pier Mannuccio Mannucci1 Speakers: Paul Coppo,2 Javier de la Rubia,3 Thorsten Feldkamp4 1. Cà Granda Maggiore Policlinico Hospital Foundation, Milan, Italy 2. Hôpital Saint-Antoine, Paris, France 3. Hospital La Fe,Read More

The Standard of Care in Relapsed Refractory CD30+ Lymphoma

The Standard of Care in Relapsed Refractory CD30+ Lymphoma

July 31, 2014 at 10:02 AM 0 comments

*Martin Hutchings Department of Hematology, Rigshospitalet, Copenhagen, Denmark *Correspondence to hutchings@dadlnet.dk Disclosure: Consultant/advisor to Genentech and Takeda/Millennium. Support: The author would like to thank Dr Caroline Charles for medical writing assistance with this manuscript. Received: 12.05.14 Accepted: 23.05.14 Citation: EMJ Hema. 2014;1:62-69. Abstract CD30-positive (CD30+) lymphomas are a heterogeneous groupRead More

Overcoming Immunodeficiency in Chronic Lymphocytic Leukaemia: Current Knowledge and Perspectives

Overcoming Immunodeficiency in Chronic Lymphocytic Leukaemia: Current Knowledge and Perspectives

July 31, 2014 at 9:58 AM 0 comments

Fabienne McClanahan,1,2 *John Gribben1 1. Barts Cancer Institute, Centre for Haemato-Oncology, Queen Mary University of London, London, UK 2. German Cancer Research Center (DKFZ), Heidelberg, Germany *Correspondence to j.gribben@qmul.ac.uk Disclosure: Fabienne McClanahan has no financial disclosures, and John Gribben is receiving Celgene Research Funding, Pharmacyclics Honoraria, and Roche Honoraria. Support:Read More

The Role of CD49d in Chronic Lymphocytic Leukaemia: Microenvironmental Interactions and Clinical Relevance

The Role of CD49d in Chronic Lymphocytic Leukaemia: Microenvironmental Interactions and Clinical Relevance

July 31, 2014 at 9:54 AM 0 comments

*Michele Dal Bo,1 Erika Tissino,1 Dania Benedetti,1 Chiara Caldana,1 Riccardo Bomben,1 Giovanni Del Poeta,2 Gianluca Gaidano,3 Francesca Maria Rossi,1 Antonella Zucchetto,1 Valter Gattei1 1. Clinical and Experimental Onco-Hematology Unit, Centro di Riferimento Oncologico, I.R.C.C.S., Aviano (PN), Italy 2. Division of Hematology, S. Eugenio Hospital and University of Rome Tor Vergata,Read More

Current Developments and Perspectives in Multiple Myeloma

Current Developments and Perspectives in Multiple Myeloma

July 31, 2014 at 9:47 AM 0 comments

*Michel Delforge,1 Stefan Knop,2 Mohamad Mohty3 1. Department of Hematology, University Hospital Leuven, Leuven, Belgium 2. Schwerpunkt Hämatologie / Onkologie, Medizinische Klinik und Poliklinik II der Universität, Würzburg, Germany 3. Hôpital Saint-Antoine, University UPMC, INSERM, Hematology Department, Paris, France *Correspondence to michel.delforge@uzleuven.be Disclosure: M. Delforge received lectures and advisory boardRead More

Autologous Stem Cell Transplantation In Multiple Myeloma: Is It Still The Right Choice?

Autologous Stem Cell Transplantation In Multiple Myeloma: Is It Still The Right Choice?

July 31, 2014 at 9:44 AM 0 comments

*Patrizia Tosi Hematology Unit, Department of Oncology and Hematology, Infermi Hospital, Rimini, Italy *Correspondence to patrizia.tosi@auslrn.net Disclosure: No potential conflict of interest. Received: 09.04.14 Accepted: 28.05.14 Citation: EMJ Hema. 2014;1:99-105. Abstract Autologous stem cell transplantation (ASCT) is considered the standard of care for multiple myeloma patients aged <65 years withRead More