Shifting Treatment Paradigms in Non-Hodgkin Lymphomas

Shifting Treatment Paradigms in Non-Hodgkin Lymphomas

August 8, 2017 at 8:29 AM 0 comments

This symposium took place on 22nd June 2017, as part of the 22nd Congress of the (EHA) in Madrid, Spain Chairperson: Dolores Caballero1 Speakers: Umberto Vitolo,2 Martin Dreyling,3 Roch Houot4 1. Department of Haematology, University Hospital Salamanca, Salamanca, Spain 2. University Hospital “Città della Salute e della Scienza di Torino”, Turin,Read More

Biosimilars for Haematologic Malignancies: The Path to Sustainable Care

Biosimilars for Haematologic Malignancies: The Path to Sustainable Care

August 8, 2017 at 8:28 AM 0 comments

This PeerCME symposium took place on 23rd June 2017, as part of the European Hematology Association (EHA) Congress in Madrid, Spain Chairperson: Paul Cornes1 Speakers: Arnold G. Vulto,2 Wojciech Jurczak3 1. Comparative Outcomes Group, Bristol, UK 2. Erasmus University Medical Centre, Rotterdam, Netherlands 3. Jagiellonian University, Krakow, Poland Disclosure: Dr Cornes reportsRead More

Patients in Focus: What’s Relevant for Chronic Myeloid Leukaemia and Philadelphia Chromosome-Positive Acute Lymphoblastic Leukaemia?

Patients in Focus: What’s Relevant for Chronic Myeloid Leukaemia and Philadelphia Chromosome-Positive Acute Lymphoblastic Leukaemia?

August 8, 2017 at 8:27 AM 0 comments

This satellite symposium took place on 22nd June 2017 as part of the 22nd European Hematology Association (EHA) Congress in Madrid, Spain Chairperson: Michele Baccarani1 Co-chair: Eduardo Olavarria2 Speakers: Hugues de Lavallade,3 Delphine Rea,4 Giovanni Martinelli1 1. University of Bologna, Bologna, Italy 2. Imperial College London, London, UK 3. King’s College Hospital,Read More

Editor’s Pick: The Role and Regulation of Quiescence in Acute Lymphoblastic Leukaemia

Editor’s Pick: The Role and Regulation of Quiescence in Acute Lymphoblastic Leukaemia

August 8, 2017 at 8:26 AM 0 comments

In this comprehensive review, emerging research regarding the role of quiescence in the causation of acute lymphoblastic leukaemia relapse is explored. This paper by Williams and Gordon provides a valuable opportunity to gain a deeper understanding of the poor prognosis for those children who relapse, and allows us to understandRead More

Thrombocytopenia: A Defect in Actin Dynamics?

Thrombocytopenia: A Defect in Actin Dynamics?

August 8, 2017 at 8:25 AM 0 comments

*Ariane S. I. Standing Department of Life Sciences, Natural History Museum, London, UK *Correspondence to a.standing@nhm.ac.uk Disclosure: The author has declared no conflicts of interest. Received: 14.03.17 Accepted: 23.05.17 Citation: EMJ Hematol. 2017;5[1]:80-86. Abstract The actin cytoskeleton plays many important roles in the lifecycle of platelets, from biogenesis from megakaryocytes,Read More

The Role of Allograft in Acute Lymphoblastic Leukaemia, Including Alternate Donors

The Role of Allograft in Acute Lymphoblastic Leukaemia, Including Alternate Donors

August 8, 2017 at 8:24 AM 0 comments

*Julian Cooney Department of Haematology, Fiona Stanley Hospital, Murdoch, Perth, Australia; University of Western Australia, Crawley, Perth, Australia *Correspondence to Julian.Cooney@health.wa.gov.au Disclosure: The author has declared no conflicts of interest. Received: 07.04.17 Accepted: 10.07.17 Citation: EMJ Hematol. 2017;5[1]:87-94. Abstract The management of acute lymphoblastic leukaemia (ALL) remains challenging. The changingRead More

Double-Hit and Triple-Hit Lymphomas: New Perspectives for Their Classification

Double-Hit and Triple-Hit Lymphomas: New Perspectives for Their Classification

August 8, 2017 at 8:23 AM 0 comments

*Cristiano Claudino Oliveira, Maria Aparecida Custódio Domingues Department of Pathology, Botucatu School of Medicine, São Paulo State University, Botucatu, São Paulo, Brazil *Correspondence to cristiano_c_oliveira@hotmail.com Disclosure: The authors have declared no conflicts of interest. Received: 10.03.17 Accepted: 10.07.17 Citation: EMJ Hematol. 2017;5[1]:95-103. Abstract In 2016, an update on the classificationRead More

Management of Adult Patients with Myelodysplastic Syndromes

Management of Adult Patients with Myelodysplastic Syndromes

August 8, 2017 at 8:22 AM 0 comments

*Nicolas Bonadies Department of Haematology and Central Haematology Laboratory, Inselspital Bern, University Hospital, University of Bern, Bern, Switzerland *Correspondence to Nicolas.Bonadies@insel.ch Disclosure: The author has declared no conflicts of interest. Received: 07.03.17 Accepted: 05.06.17 Citation: EMJ Hematol. 2017;5[1]:104-112. Abstract The myelodysplastic syndromes (MDS) form a heterogeneous group of clonal disordersRead More

Different Therapeutic Interventions and Mechanisms of Action of Antisickling Agents Currently in Use in Sickle Cell Disease Management

Different Therapeutic Interventions and Mechanisms of Action of Antisickling Agents Currently in Use in Sickle Cell Disease Management

August 8, 2017 at 8:21 AM 0 comments

*Ngozi Awa Imaga, Oluwole Taiwo Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, University of Lagos, Lagos, Nigeria *Correspondence to noaimaga@gmail.com Disclosure: The authors have declared no conflicts of interest. Received: 11.04.17 Accepted: 10.07.17 Citation: EMJ Hematol. 2017;5[1]:113-117. Abstract Sickle cell disease is a genetic disorder causedRead More

The Pivotal Role of Proteasome Inhibition in Myeloma Treatment

The Pivotal Role of Proteasome Inhibition in Myeloma Treatment

July 28, 2017 at 8:30 AM 0 comments

This symposium took place on 26th March 2017, as a part of the European Group for Blood and Marrow Transplantation (EBMT) Annual Meeting in Marseille, France Chairperson: Meletios Dimopoulos1 Speakers: Nikhil C. Munshi,2 Pieter Sonneveld3 1. Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece 2. Harvard Medical School;Read More