Managing Ulcerative Colitis – The Guidelines and Beyond

Mitchell RKL Lie, C Janneke van der Woude

Department of Gastroenterology, Erasmus University Hospital, Rotterdam, the Netherlands

Disclosure: No potential conflict of interest.
Received: 17.09.13 Accepted: 19.11.13
Citation: EMJ Gastroenterol. 2013;1:82-91.


Management guidelines offer clinicians clear, evidence-based and often succinct treatment advice. For ulcerative colitis these guidelines describe the use of 5-ASA, corticosteroids, thiopurines, cyclosporine, and anti-TNF╬▒ therapies. However, guidelines do have some drawbacks, mainly a lack of concrete advice concerning patients resistant to these aforementioned therapies. This review gives a short overview of current guidelines and addresses treatment alternatives for conventional therapies.

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