Mitchell RKL Lie, C Janneke van der Woude
Department of Gastroenterology, Erasmus University Hospital, Rotterdam, the Netherlands
Disclosure: No potential conflict of interest.
Received: 17.09.13 Accepted: 19.11.13
Citation: EMJ Gastroenterol. 2013;1:82-91.
Management guidelines offer clinicians clear, evidence-based and often succinct treatment advice. For ulcerative colitis these guidelines describe the use of 5-ASA, corticosteroids, thiopurines, cyclosporine, and anti-TNFα therapies. However, guidelines do have some drawbacks, mainly a lack of concrete advice concerning patients resistant to these aforementioned therapies. This review gives a short overview of current guidelines and addresses treatment alternatives for conventional therapies.