Current Concepts in Coronary Artery Spasm

*†Ozan M. Demir,1 †Jonathan Hudson,2 William Wallis1

1. Department of Cardiology, Imperial College Healthcare NHS Trust, London, UK
2. Department of Cardiology, Watford General Hospital, Hertfordshire, UK
*Correspondence to
†Both authors contributed equally

Disclosure: The authors have declared no conflicts of interest.
Received: 09.03.16 Accepted: 23.08.16
Citation: EMJ Cardiol. 2016;4[1]:96-102.


Coronary artery spasm is an abnormality of coronary vascular smooth muscle contraction that is associated with significant morbidity and mortality. The underlying pathophysiological process has remained unclear since Myron Prinzmetal described it in 1959. This article reviews current literature of the pathogenesis and outlines clinical features, diagnosis, and treatment options.

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