Pembrolizumab Improves Survival as a Second-Line Treatment for Urothelial Cancer

Pembrolizumab Improves Survival as a Second-Line Treatment for Urothelial Cancer

Urology March 27, 2017 at 8:48 AM 0 comments

PEMBROLIZUMAB, a highly selective, humanised monoclonal antibody targeting programmed cell death 1 (PD-1), has a superior safety profile and improved survival rates compared with chemotherapy when used as second-line treatment for advanced urothelial carcinoma, results from a recent Phase III trial revealed. This open-label, international trial featured 542 patients withRead More

Promising Results from Phase II Trial of Renal Cancer Drug

Promising Results from Phase II Trial of Renal Cancer Drug

Urology March 27, 2017 at 8:47 AM 0 comments

RESULTS published from a Phase II clinical trial have shown the potential of the investigational drug savolitinib in the treatment of c-MET-driven papillary renal cell carcinoma. Renal cell cancer is the most common type of kidney cancer and papillary renal cell carcinoma is the second most histologic subtype. This subtypeRead More

The First Successful Robot-Assisted Retinal Vein Cannulation

The First Successful Robot-Assisted Retinal Vein Cannulation

Innovations March 20, 2017 at 8:58 AM 0 comments

A REVOLUTIONARY treatment has been developed for the surgical dispersal of retinal vein occlusion clots. The procedure would not have been possible without the aid of a specialist robotic device, which was custom-made by mechanical engineering researchers from the Katholieke Universiteit Leuven, Leuven, Belgium, and has enabled surgeons at theRead More

Scientists Develop Bioprinting Technology Capable of Synthesising Human Skin

Scientists Develop Bioprinting Technology Capable of Synthesising Human Skin

Innovations March 20, 2017 at 8:56 AM 0 comments

HUMAN skin has been successfully synthesised using a three-dimensional (3D) bioprinter. Researchers at the Universidad Carlos III de Madrid, Madrid, Spain, have developed an innovative new bioprinting method which could revolutionise tissue grafting, organ transplantation, pharmaceutical drug development, and cosmetic testing. Previously, scientists successfully demonstrated the effective generation of plasma-basedRead More

An Association Between Klotho Deficiency and Kidney Function

An Association Between Klotho Deficiency and Kidney Function

Nephrology March 13, 2017 at 9:15 AM 0 comments

STRONG links have been discovered between the soluble protein Klotho and the decline in kidney function. The Klotho protein, whose gene is named after the Greek goddess believed to be responsible for birth and death, has two types: a secreted ‘soluble Klotho’ which circulates around the blood and a membrane-boundRead More

Model Kidneys Give New Hope to Researchers

Model Kidneys Give New Hope to Researchers

Nephrology March 13, 2017 at 9:13 AM 0 comments

AN ANIMAL testing alternative may soon be available after researchers at Bingham University, Binghamton, New York, USA, achieved a breakthrough in the development of a model kidney. Prof Gretchen Mahler and Dr Courtney Sakolish, Department of Biomedical Engineering, Binghamton University, Binghamton, New York, USA, have created a multi-layered, reusable, microfluidicRead More

Osteoarthritis and Back Pain: The Weather Plays No Part

Osteoarthritis and Back Pain: The Weather Plays No Part

Rheumatology March 6, 2017 at 3:11 PM 0 comments

HISTORICALLY, symptoms associated with osteoarthritis and back pain have been thought to be exacerbated by adverse weather conditions. However, research conducted at The George Institute of Global Health, Sydney, Australia, provides new evidence demonstrating that factors including temperature, humidity, atmospheric pressure, precipitation, and wind direction have no impact on theRead More

Rheumatoid Arthritis Joint Pain Promoted by Novel T Cell

Rheumatoid Arthritis Joint Pain Promoted by Novel T Cell

Rheumatology March 6, 2017 at 3:10 PM 0 comments

A UNIQUE type of T cell has been discovered in patients with rheumatoid arthritis (RA). Research conducted at the Brigham and Women’s Hospital (BWH), Boston, Massachusetts, USA, has recognised the pivotal role these cells play in mediating the damaging immune response accountable for the joint inflammation associated with RA. ExistingRead More

Vaccine Developed for Bee Stings

Vaccine Developed for Bee Stings

Allergy & Immunology February 27, 2017 at 2:21 PM 0 comments

A HIGHLY effective vaccine for European honeybee stings has been developed by researchers from Adelaide, South Australia; the success of this vaccine has raised the possibility of developing new treatments for a variety of other pollen, plant, and insect allergies. The development of new vaccines is highly pertinent due toRead More

Interleukin-33 Found to Influence Allergy Sensitivity in Neonatal Lungs

Interleukin-33 Found to Influence Allergy Sensitivity in Neonatal Lungs

Allergy & Immunology February 27, 2017 at 2:19 PM 0 comments

A PROTEIN produced by white blood cells, interleukin-33 (IL-33), is a core driver of allergic sensitivity in the lungs of newborns according to the results of a recently published study; this discovery could aid the treatment of allergy and asthma in neonates and young children. The study’s lead author, ProfRead More